Meaning Of Asymptomatic Hyperuricemia

Hyperuricemia is an abnormally high level of uric acid in the blood in the ph conditions of body fluid uric acid exists largely as urate the ion form.

Meaning of asymptomatic hyperuricemia. Patients with asymptomatic hyperuricemia had significantly higher average number of risk factors lower hdl cholesterol and higher creatinine and triglycerides levels lower ejection fraction ef. The four phases of gout include asymptomatic hyperuricemia acute gouty arthritis. Debate persists regarding the benefit of treating all cases of asymptomatic hyperuricemia and hence unsurprisingly there are no clear clinical practice guidelines from our country.

Patients receiving no urate lowering. Serum uric acid concentrations greater than 6 mg dl for females 7 mg dl for men and 5 5 mg dl for youth under 18 years old are defined as hyperuricemia. This is known as asymptomatic hyperuricemia.

Gout uric acid renal diseases and uric acid nephrolithiasis are discussed separately. For years hyperuricemia has been identified with or thought to be the same as gout but uric acid has. The amount of urate in the body depends on the balance between the amount of purines.

The definition and management of asymptomatic hyperuricemia has been an area of controversy for many decades. Debate persists regarding the benefit of treating all cases of asymptomatic. Definition uric acid a product of purine metabolism is degraded in most mammals by the hepatic enzyme urate oxidase uricase to more highly soluble allantoin which is freely excreted in the urine.

See clinical manifestations and diagnosis of gout and treatment of gout flares and pharmacologic urate lowering therapy and treatment of tophi in patients with. The definition and management of asymptomatic hyperuricemia has been an area of controversy for many decades. Asymptomatic hyperuricemia until larger placebo controlled studies are completed.

A recent large population based retrospective cohort study with 16 186 patients with hyperuricemia examined the association of urate lowering therapy treatment with kidney function decline 12 the cohort was divided into 3 groups. Hyperuricemia is defined as a plasma uric acid concentration 6 8 mg dl. Although hyperuricemia isn t a disease if uric acid levels remain high over.